FPGEE for National Association of Boards of Pharmacy (NABP) Practice Exam

Which category indicates that risk cannot be ruled out during pregnancy?

1. Category A

2. Category B

3. Category C

4. Category D

The correct answer is: Category C

The correct answer indicates that Category C is the classification for drugs where risk to the fetus cannot be ruled out. In this category, studies in animals may show adverse effects, but there are no controlled studies in pregnant women. Therefore, the potential benefits of using the drug might warrant its use in pregnant women despite potential risks. This underscores the importance of weighing the risks and benefits when considering medications for pregnant patients, as healthcare providers need to ensure that medication use does not present unacceptable risks to the developing fetus. In contrast, Category A drugs have been tested in pregnant women and show no risk to the fetus, while Category B drugs show no risk in animal studies and have not been tested in pregnant women, or have shown no adverse effects in humans. Category D drugs, conversely, provide evidence of human fetal risk but may be used in life-threatening situations where no alternatives are available. This categorization highlights the importance of evaluating each medication's potential impact on pregnancy.