FPGEE 2026 Practice Exam for NABP – The Complete All-in-One Guide to Exam Success!

The primary function of a levigating agent is to aid in the initial dispersion of insoluble particles. Levigation is a process where solid particles are dispersed in a liquid to form a smooth and uniform paste, which is essential in the formulation of certain pharmaceuticals, such as ointments and creams. The levigating agent forms a wetting layer around the insoluble particles, making it easier to mix and reduce particle size, thus improving the distribution of active ingredients within the formulation. This is particularly important in achieving a consistent dosage and enhancing the overall homogeneity of the product.

In contrast, other options refer to different roles that do not pertain to the specific function of a levigating agent. For instance, preservatives are used to prevent microbial growth, while agents that increase bioavailability focus on enhancing the absorption of drugs into systemic circulation. Enhancing taste is relevant for oral formulations’ palatability but does not relate to the dispersion of insoluble particles. Therefore, the role of a levigating agent is distinctly linked to facilitating the preparation of uniform mixtures rather than functions associated with preservation, absorption, or taste enhancement.